Motorists are being warned to expect significant disruption, with the A4103 (Hereford to Worcester Road) closed at Leigh Sinton this weekend.
Work will be carried out this weekend in Leigh Sinton, with motorists advised to use alternative routes.
The A4103 will be closed at Dragons Cross, from the junction with the U62243 Lynn Close to the junction for U63448 Dragons Lane.
Signage has been placed along the route, including on Commercial Road in Hereford, in anticipation of the work that will take place this weekend.
The closure is for resurfacing and white lining, as well as carriageway planning.