Emergency services remain at the scene of a fire at a premises on Severn Road, Treforest Industrial Estate, Rhondda Cynon Taff.
This follows reports of an explosion at a property shortly after 7.00pm last night.
Following a search of the site officers have located a body.
While identification has not yet been completed, specially trained officers are supporting the family of the missing individual.
Detective Superintendent Richard Jones of South Wales Police said:
“Our thoughts are with the family of the missing person.
“Now that the fire has been brought under control, we will move to the investigative phase to find out what caused this explosion and subsequent fire.
“Roads are gradually being re-opened although some roads and businesses in the area will still be affected.
“I want to thank local residents and businesses for their patience and understanding while this incident is being dealt with.”
A joint investigation team from South Wales Fire and Rescue Service and South Wales Police, in conjunction with the Health and Safety Executive, are now on site to determine the cause of the fire.